The actor plays an HIV positive man who smuggles medication into the US in the 80s and his performance, which is already generating Oscar buzz, wowed the Toronto crowd.

Matthew lost nearly 50 pounds to star in the true story of Ron Woodroof, but told the film festival audience that shedding the pounds wasn’t the hard part.

“That was the easy decision,” he said. “I would have been embarrassed standing here looking like I do now playing the guy. That really wouldn’t have worked.”

Jared Leto also stars in the film as a drug-addicted transsexual and revealed that the chance to work with Matthew was one of the reasons he signed up.

Matthew McConaughey is doing something spectacular with his life, with his career, and I wanted to be a part of that,” he said.

“He’s doing some of the most incredibly inspiring work. That was a huge part of my decision. I said, ‘If he’s willing to walk down this path, I gotta get in the ring with him. That’s somebody I want to dance with’.”

Sean Penn has been spotted filming in London

More in News (10 of 20 articles)

Penn shooting Gunman in London Read More